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Product Usage: This product is intended as a research chemical only. This designation permits the use of research chemicals strictly for in vitro testing and laboratory research, but not for human or animal.. This product should only be handled by licensed, qualified professionals. All information available on this website is for educational purposes only. This product is not a drug, food, or cosmetic and may not be misbranded, misused, or mislabeled as such. Acknowledged to the Terms and Conditions, the customer hereby agrees to take full responsibility on how to use the product.
Acetyl Hexapeptide-1, also known as Melitane, is a biomimetic peptide antagonist of the α-MSH (α-Melanocyte-Stimulating Hormone). The α-MSH regulates melanin synthesis via the activation of its receptor MC1-R. Because of its affinity with the receptor MC1-R, Acetyl Hexapeptide-1 can be used as a natural photo-protector and as an inflammation modulator.
By stimulating the melanin synthesis through a natural pathway and by preventing the excessive production of pro-inflammatory cytokines, Melitane® represents an ideal complement to the skin’s own levels of natural melanin and strengthens the skin’s defenses against the harmful effects of sunshine and reduces the potential pro-inflammatory consequences.
INCI name: Acetyl Hexapeptide-1
CAS#: 448944-47-6
Formula: C43H59N13O7
Sequence: Ac-Nle-Ala-His-D-Phe-Arg-Trp-NH2; XAHFRW
M.W.: 870.01 g/mol
Synonyms: Melitane®
Storage: keep away from moisture, -20C for 3 years
Even if gray hair can be a fashion statement, many people desire lustrous colorful hair. As we age, the hair follicles produce less melanin, the pigment responsible for hair color, so progressively hair become gray.
Hair follicles produce the hair fiber that becomes pigmented as a result of melanin synthesis and its transfer from melanocytes into keratinocytes. To fight back hair graying, Unipex has developed Acetyl Hexapeptide-1, a biomimetic peptide derived from alpha-MSH.
Acetyl Hexapeptide-1 (sequence: Ac-Nle-Ala-His-D-Phe-Arg-Trp-NH2; XAHFRW) stimulates melanin synthesis by melanocytes and also favors melanin transfer from melanocytes into keratinocytes. Moreover, Acetyl Hexapeptide-1 obtains outstanding results in ex vivo experiments on hair.
It decreases the number of white and low-pigmented cells and increases the number of moderate and highly-pigmented cells in hair bulbs. Acetyl Hexapeptide-1 is also used in a peptide-based MelinOIL™ for preparing skin for sun exposure and protection from UV-induced photoaging.
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At QUALITIDE, we aim to make your shopping experience simple and smooth. Here’s how we handle shipping: Processing Time We process all orders within 0 to 1 business day. Orders placed after business hours, on weekends, or on holidays will be processed the next business day. Delivery Time Once processed, delivery takes 2 to 3 business days, depending on your location and the shipping carrier. Total Delivery Time From placing your order to receiving it, the total time is 2 to 4 business days, including both processing and shipping.
All articles and product information provided on this website are for informational and educational purposes only. The products offered on Qualitides are intended solely for in-vitro research purposes. In-vitro studies ("in glass" studies) are conducted outside of the body. These products are not medicines or drugs and have not been evaluated or approved by the FDA to prevent, treat, diagnose, or cure any medical condition, ailment, or disease. Any form of bodily introduction or administration of these products into humans or animals is strictly prohibited by law. By using this website, you acknowledge and agree to comply with all applicable regulations and restrictions related to the products provided by Qualitides.
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