Eyelitide™ Complex Solution

Introduction

Eyelitide™ Complex Solution is a high-end cosmetic peptide composite for the eye area containing 7 highly active essential peptides, which can comprehensively solve eye problems (eye wrinkles, eye bags and dark circles). 

• Dipeptide Valyl-Tryptophane (aka Syn-Ake®) is a peptide that promotes the drainage of fluid that collects under the eye creating bags and puffiness.
• Lipopeptide Pal-GQPR (Matrixyl™) is another peptide that decreases inflammation, improves skin elasticity and firmness, and reduces fine lines and wrinkles.
• Tripeptide-5 (aka Syn-Coll®) is highly bioactive, deeply skin penetrating peptide (palmitoyl tripeptide-5) able to activate tissue growth factor (TGF-beta) that stimulates collagen synthesis in the skin.
• Hesperidin Methyl Chalcone (bioflavonoid) is a natural ingredient derived from flavonoid hesperidin found in citrus fruits like grapefruit and oranges. This rather newly discovered ingredient helps to strengthen capillaries and veins as well to improve lymphatic drainage and circulations which tones the delicate under eye area.

These highly active biologics work synergistically and therefore significantly improve skin texture and increase skin elasticity within 1 to 3 skin growth cycles; two ACE enzyme inhibitor peptides fight eye face edema and solve eye bags and dark circles in 15 days.

Mechanism of Action

•        Anti-aging and anti-wrinkle

High content of instant anti-wrinkle active peptide ingredients: 1) Tripeptide reduces wrinkles by inhibiting muscle contraction. Blocking the binding of acetylcholine to receptors eventually leads to receptor closure. In the closed state, sodium ions cannot be released, so the muscles relax; 2) Hexapeptide participates in the competition for SNAP-25 at the site of the melt-vesicle complex, thereby affecting the formation of the complex. The melt-vesicle complex is slightly unstable, and the vesicle cannot effectively release neurotransmitters, which leads to weakened muscle contraction and prevents the formation of wrinkles. Hexapeptide-3 can reduce the depth of wrinkles caused by facial expression muscle contraction, especially in the forehead and around the eyes.

Active peptide ingredients to improve skin quality: 1) Palmitoyl-pentapeptide micro-collagen chemically synthesized natural collagen micro-fragments, specifically acting on dermal cells, stimulating collagen synthesis, and maintaining the elastic surface of the skin; 2) Palmitoyl-tripeptide promotes collagen and polysaccharide synthesis; 3) Pal-tetrapeptide reduces the level of IL6 in aging, thereby achieving the goal of re-maintaining the balance of cytokines in the skin to achieve skin care.

•           Eye Bag Removal

1) Acetyl tetrapeptide inhibits ACE activity and improves blood circulation through antihypertensive effects; inhibits glycosylation; inhibits vascular permeability and prevents water from leaking from blood vessels; fights edema and relieves eye bags;

2) Dipeptide inhibits ACE enzyme, enhances lymphatic circulation and fights edema. 

Efficacy and application:

Eye care products for removing eye bags and eye wrinkles, repairing eye contour, etc.

Product Specifications

As a professional beauty peptide supplier, after years of research and summary, Qualitide ^™ has a complete set of beauty peptide production processes and management systems. We produce peptides strictly in accordance with standards, and each batch of products undergoes strict quality inspections to ensure the high quality, high stability and high activity of the products. The raw material Qualitide provides to customers is compound eye peptide solution. The packaging specifications are 1 fl oz/bottle and 250mL/bottle.

INCI Ingredients: Glycerin, Butylene, Glycol, Water, Carbomer, Tween-20, Palmitoyl Tripeptide, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-7, Tripeptide, Hexapeptide, Dipeptide, Acetyl Tetrapeptide

Appearance: Opalescent gel

Color: Off-white

Water content: 20~30%

pH: 4.0~6.0 

Safety Tests

In vitro and in vivo tests show that the Eyelitide-Plex^TM  did not show any cytotoxicity, skin irritation, allergy and eye irritation.

Usage and Dosage

Eyelitide-Plex^TM can be added in the final stage of cosmetic production, and the preparation temperature should be below 40°C. Based on the concentration of the Eyelid complex solution, 2~5% is recommended as the final product content to achieve significant anti-wrinkle and anti-eye bag activity. In order to avoid secondary microbial contamination, it should be used immediately after opening the cap.

 Storage and Shelf Life

The compound eye peptide solution must be stored in a cool, dark and clean place to ensure a shelf life of at least 12 months. For long-term storage, it is recommended to store at 4°C, and the shelf life can be extended to at least 18 months.