Tetrapeptide-21 (TEGOPep4-17)

What is Tetrapeptide-21?
Tetrapeptide-21 (GEKG peptide) is a synthetic peptide that mimics the structure of fragments from extracellular matrix (ECM) proteins such as collagens I-V, elastin, and pro-elastin. This peptide boosts the production of essential ECM components like collagen, hyaluronic acid, and fibronectin, making it a powerful anti-aging and skin-regeneration ingredient.

Key Benefits of Tetrapeptide-21

1. Collagen Production Boost:
   Tetrapeptide-21 enhances gene expression responsible for collagen synthesis by dermal fibroblasts, increasing production up to 2.5 times. This results in firmer, more elastic skin and reduced appearance of fine lines and wrinkles.

2. Hydration and Volume:
   By stimulating hyaluronic acid production, Tetrapeptide-21 improves skin hydration, elasticity, and volume, helping to create a plump and youthful appearance.

3. Improved ECM Network:
   The peptide increases the production of fibronectin glycoprotein, which acts as a binding agent for ECM components like collagen, elastin, and hyaluronic acid. This creates a stronger, more connected matrix for smoother, more resilient skin.

4. Skin Regeneration:
   As a fragment of ECM proteins, Tetrapeptide-21 mimics natural processes in the skin to stimulate repair and regeneration, accelerating wound healing and improving skin texture.

5. Anti-Aging Effects:
   This peptide reduces skin roughness, fights fine lines and deep wrinkles, and enhances the overall condition and structure of the skin, revealing a more youthful and supple complexion.

Functions of Tetrapeptide-21

• Stimulates collagen synthesis
• Boosts hyaluronic acid and fibronectin production
• Enhances skin elasticity and hydration
• Reduces fine lines, wrinkles, and skin roughness
• Improves overall skin condition and structure

Synonyms

• TEGO® Pep 4-17

Applications

Tetrapeptide-21 is widely used in:

• Anti-aging creams and serums
• Hydrating skincare formulations
• Skin repair and regeneration products
• Products targeting fine lines, deep wrinkles, and roughness

Technical Highlights

• Peptide Sequence: Gly-Glu-Lys-Gly (GEKG)
• Role in ECM: Mimics fragments of collagen, elastin, and other ECM proteins
• Proven Efficacy: Increases gene expression for collagen and ECM components

Why Choose Tetrapeptide-21?

Tetrapeptide-21 is a safe, scientifically validated ingredient that delivers visible improvements in skin elasticity, hydration, and smoothness. With its ability to mimic natural regenerative processes, it is a must-have in any high-performance anti-aging skincare formula.

Incorporate Tetrapeptide-21 into your skincare routine for a firmer, more radiant, and youthful-looking complexion.